RECOMB Satellite Conference on Open Problems in Algorithmic Biology

Event Dates

Aug 27, 2012 - Aug 29, 2012

Location

St. Petersburg, Russia

Submission Deadline

Apr 27, 2012

CALL FOR PAPERS

RECOMB Satellite Conference on Open Problems in Algorithmic Biology

(RECOMB-AB)

August 27-29, 2012

St. Petersburg, Russia

http://bioinf.spbau.ru/ab2012

recombab2012 at gmail dot com

OVERVIEW:

The First RECOMB Satellite Conference on Open Problems in Algorithmic

Biology (RECOMB-AB) will be held August 27-29, 2012 in St. Petersburg,

Russia. This workshop brings together leading researchers in the

mathematical, computational, and life sciences to discuss current

challenges in computational biology, with an emphasis on open

algorithmic problems. The program will consist of invited speakers,

contributed speakers, posters, and discussion panels.

Saint Petersburg (formerly known as Leningrad) is Russia’s second

largest city. The large historic center of Saint Petersburg, threaded

with canals dotted with baroque bridges, is a UNESCO World Heritage

site. Its Hermitage Museum, housed in the Winter Palace (formerly

called the Palace of the Russian Tsars), is one of the world’s

greatest collections of art.

KEYNOTE SPEAKERS:

Max Alekseyev (University of South Carolina)

Vineet Bafna (University of California, San Diego)

Mikhail Gelfand (Russian Academy of Sciences and Moscow State University)

Sorin Istrail (Brown University)

Richard Karp (University of California, Berkeley)

Bernard Moret (École Polytechnique Fédérale de Lausanne)

Stephen O’Brien (Saint Petersburg University)

Pavel Pevzner (University of California, San Diego)

Marie-France Sagot (INRIA, Université Lyon 1)

Cenk Sahinalp (Simon Fraser University)

Ron Shamir (Tel Aviv University)

Glenn Tesler (University of California, San Diego)

Tandy Warnow (The University of Texas at Austin)

Michael S. Waterman (University of Southern California)

THEME AND SCOPE:

RECOMB-AB aims to discuss recent advances and present open algorithmic

problems in different areas of life sciences. Today, life sciences are

in the midst of a major paradigm shift driven by computational

sciences. RECOMB-AB emphasizes that this is a two-way street: while

life sciences have greatly benefited from new computational ideas,

they also are a major source of new open problems and inspiration for

computational sciences. RECOMB-AB brings together leading researchers

in the mathematical, computational, and life sciences to discuss

interesting, challenging, and well-formulated open problems in

algorithmic biology.

Many areas of computational sciences started as an attempt to solve

applied problems and later became more theoretically-oriented. These

theoretical aspects may be very valuable even if they stray away from

the applied problems that originally motivated them. Thus, RECOMB-AB

is interested in a wide range of well-formulated open problems. Some

of them may be rather theoretical and have limited biological

application. The solutions of others might provide valuable tools for

biologists or might lead to new biological discoveries. This blend of

theoretical and applied problems is a fascinating feature of

algorithmic biology.

The discussion panels at RECOMB-AB will also address the worrisome

proliferation of ill-formulated computational problems in

bioinformatics. While some biological problems can be translated into

well-formulated computational problems, others defy all attempts to

bridge biology and computing. This may result in computational biology

papers that lack a formulation of a computational problem they are

trying to solve. While some such papers may represent valuable

biological contributions (despite lacking a well-defined computational

problem), others may represent computational “pseudoscience.”

RECOMB-AB will address the difficult question of how to evaluate

computational papers that lack a computational problem formulation.

Open problems should address a problem of interest in Biology, whose

solution may depend on development of new ideas in Computing, or

problems of interest in Computing that were initially motivated by

Biology. Open problems may be completely new; they may be problems

that were studied in the past but without a precise formulation as an

algorithmic problem; or they may be new and improved self-contained

formulations of previously published problems.

Topics of interest include, but are not limited to,

* Machine learning, statistical, combinatorial, and other algorithms

in biology

* Molecular sequence analysis

* Molecular evolution

* Gene expression

* Biological networks

* Sequencing and genotyping techniques

* Genomics

* Population genetics

* Systems biology

* Bio-imaging

* Molecular structural biology

* Proteomics

OPEN PROBLEMS IN ALGORITHMIC BIOLOGY PROJECT:

Selected speakers (invited and contributed) will be invited to

participate in an article on Open Problems in Algorithmic Biology, to

be published in the Journal of Computational Biology in Fall

2012. This multi-author article will be a compilation of the problems

posed in the abstracts and invited talks.

CALL FOR PARTICIPATION:

RECOMB-AB will have a somewhat unusual format. In addition to research

abstracts, RECOMB-AB will showcase open problems in algorithmic

biology. We invite submissions in two categories: Algorithmic Biology

Open Problems, and Algorithmic Biology Research Abstracts. Submissions

should be submitted through the links provided on the RECOMB-AB

website and must be received by April 27, 2012.

Algorithmic Biology Open Problems. Each submission should cover a

single well-formulated open problem in algorithmic biology. Each

submission should be self-contained and should start from a statement

of biological problem and end with a well-formulated computational

problem addressing the biological problem. Authors should include the

motivation for studying the problem and any known partial or

conjectured solutions of the problem. A single submission may include

multiple computational problems motivated by the same biological

problem. Authors of selected papers will be invited to present their

problem at RECOMB-AB either as a talk or as a poster. Selected authors

will also be invited to participate in a multi-author article on Open

Problems in Algorithmic Biology, to be published in the Journal of

Computational Biology.

Algorithmic Biology Research Abstracts. Unpublished work and recently

published work will both be considered. If the work is published,

please include it in the references. Authors of selected papers will

be invited to present their paper at RECOMB-AB either as a talk or as

a poster. Abstracts will be distributed to conference participants,

but there is no formal publication through the conference.

PREPARATION OF ABSTRACTS:

Abstracts should be submitted via the conference website in PDF

format. All abstracts should be in English. Abstracts consist of up to

two pages of text (plus cover page, references, figures, and tables,

which do not count towards the two pages). Please see the conference

website for further details.

KEY DATES:

Abstract submission deadline Friday April 27, 2012

Notification of acceptance Friday May 18, 2012

Request for visa Friday May 25, 2012

Final abstract due Friday June 15, 2012

Registration period To be announced

Conference August 27-29, 2012

(arrival on August 26)

PROGRAM COMMITTEE:

Glenn Tesler (University of California, San Diego) (Chair)

Pavel Pevzner (University of California, San Diego) (Co-chair)

Max Alekseyev (University of South Carolina)

Guillaume Bourque (McGill University)

Michael Brudno (University of Toronto)

Mark Chaisson (Pacific Biosciences)

Francis Chin (University of Hong Kong)

Dannie Durand (Carnegie Mellon University)

Eran Halperin (Tel Aviv University)

Uri Keich (University of Sydney)

Alexander Kulikov (Steklov Institute of Mathematics at St. Petersburg and St. Petersburg Academic University)

Laxmi Parida (IBM Research)

Alkes Price (Harvard University)

Mona Singh (Princeton University)

Jens Stoye (Bielefeld University)

Haixu Tang (Indiana University)

Olga Troyanskaya (Princeton University)

Nikolay Vyahhi (St. Petersburg Academic University)

Kira Vyatkina (St. Petersburg Academic University)

ORGANIZING COMMITTEE:

Alexander Kulikov (Steklov Institute of Mathematics at St. Petersburg and St. Petersburg Academic University) (Chair)

Nikolay Vyahhi (St. Petersburg Academic University) (Co-chair)

Max Alekseyev (University of South Carolina)

Mikhail Gelfand (Moscow State University)

Alexander Omelchenko (St. Petersburg Academic University)

Kira Vyatkina (St. Petersburg Academic University)